SNRIs may increase your bleeding risk, particularly when you're taking other medications that also increase the risk of bleeding, such as ibuprofen (Advil, Motrin IB), aspirin, and blood thinners. Sometimes children, teenagers, and young adults under age 25 may experience an increase in suicidal thoughts or behavior when taking antidepressants. ![]() ![]() Other possible side effects include fatigue, constipation, insomnia, changes in sexual function, and loss of appetite. The most common side effects of SNRIs are nausea, dry mouth, dizziness, headache, and excessive sweating, per the Mayo Clinic. People with major depressive disorder - a serious medical condition that negatively affects how a person feels, thinks, and acts - may be prescribed a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs), which keep norepinephrine and serotonin from being reabsorbed and stored in nerve endings, per Mental Health America.Īccording to Mayo Clinic, commonly prescribed SNRIs include: ![]() Low levels of norepinephrine have been associated with low mood.
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